Despite their therapeutic potential, peptides continue to present a complex puzzle when it comes to sustained delivery, especially within the constraints of the intravitreal and suprachoroidal spaces. This workshop will explore why sustained peptide delivery has remained elusive, and what formulation innovations, especially around suspension dynamics, molecular engineering, and modular platforms, may finally unlock success.

Key Topics to be Explored:

• Why peptide therapeutics have failed to achieve long term-delivery in the vitreous, and how new strategies are beginning to shift the paradigm
• Investigate how stabilizing peptides in suspension can mitigate degradation, reduce burst release, and improve duration without requiring encapsulation or PEGylation
• Modifying peptide structure or charge to enhance targeting and penetration without compromising bioactivity
• Discuss emerging modular formulation systems that allow developers to tailor peptide delivery to the needs of specific compounds, accelerating translation from discovery to clinic