Patrick Ruane

Chief Operating Officer Re-Vana Therapeutics

Patrick has dedicated over twenty years to the advancement of sustained release drug delivery systems, specializing in various medical disciplines such as Cardiovascular, Ophthalmology, Gastrointestinal, Ear Nose and Throat, Transdermal, and Surgical. His expertise lies in achieving controlled and prolonged release of Active Pharmaceutical Ingredients from biodegradable polymeric platforms integrated into drug-device combination products.

Patrick held key positions at prominent pharmaceutical companies, serving as CTO at Allay Therapeutics and Chrono Therapeutics, and as VP of R&D at CV Ingenuity, later acquired by Covidien. He is dedicated to improving patient care through novel sustained drug delivery systems, leveraging his multidisciplinary expertise to advance the field and enhance treatment options, ultimately improving patient outcomes.

Patrick, a highly skilled physical-organic photochemist, has made significant contributions to academic and patent literature through extensive publications. With undergraduate degrees from The Galway-Mayo Institute of Technology and Trinity College Dublin, he pursued a Ph.D. from University College Dublin. His expertise led him to research Reactive Intermediates and Reactive Oxygen Species (ROS) using Laser Flash Photolysis during a fellowship at The University of Toronto. At The Johns Hopkins University, he employed Time-resolved Infrared spectroscopy to investigate organic chemistry reactions and developed a controlled release caged system for nitric oxide delivery. His groundbreaking research at The Ohio State University resulted in the commercialization of a product for pathogen inactivation in human blood products. Patrick’s work bridges scientific research and practical applications, demonstrating his dedication and talent in advancing knowledge and addressing real-world challenges.

Seminars

Wednesday 20th January 2027
Harnessing OcuLief Technology to Improve Retinal Drug Durability, Reduce Treatment Burden & Enhance Patient Outcomes
11:30 am
  • Explore how Re-Vana’s OcuLief technology enables a high-payload liquid formulation to be delivered through a conventional intravitreal injection and rapidly transformed into a solid implant using visible light, providing sustained drug release directly within the eye
  • Understand how OcuLief is designed to overcome the limitations of frequent intravitreal injections by extending therapeutic durability, maintaining local drug exposure, and supporting improved patient adherence in retinal disease management
  • Assess the clinical, manufacturing, and regulatory considerations associated with translating light-activated sustained-release implants into practice and discover what is required to achieve broad clinical adoption and commercial success in ophthalmology
Patrick Ruane, Re-Vana Therapeutics - Speaker 5th Ophthalmic Drug Delivery Summit